Demetri Martin and Zach Galifianakis have good bits with instruments. I've seen other people try it and so far no one has pulled it off as well as these two.
I listen to Dane Cook's CD's a lot but he can get really annoying when he goes off on a ten minute side story and has to go back to the joke I already forgot about.
Daniel Tosh is good too. I've only seen a few of his specials but I've been watching a lot of Tosh.0 lately and it's pretty good.
I like Jim Gaffigan too. He uses his awkwardness well.
I can't stand Blue Collar Comedy. All my friends rave about that :bou::bou::bou::bou: and I'm like "Really? It's been forever since that :bou::bou::bou::bou: came out and you're still talking about it?" That ass who uses puppets is pretty annoying too.