I agree.
I had become so tired of the GTA formula that I didn't pick up Red Dead Redemption on release. I didn't even finish the first island on GTA IV I was that bored with it.
I bought RDR on an impulse buy for £15. It is simply a beautiful game. It does tread a similar GTA path with the mission layout but the world you are presented with is so rich and satisfying... I've spent hours simply scouring the plains skinning animals... or sat playing Texas Hold 'Em. I was genuinely upset when some scumbag thief killed my horse.
On to games that disappointed me... I wasn't happy with the feeling that Skyward Sword left me with. I enjoyed a lot of the elements but story-telling in games has come such a long way over the past few years that SS felt kind of empty. When you compare it to games like Uncharted 3 then you realise that Nintendo have really been left behind in that respect.