I've played through FFX 13 times, with several files completely maxed out in terms of items, "levels" and stats, etc...
Morrowind has been played through at least five times
I have logged around 220 hours on my FFTA file
SO3 took an ungodly amount of time due to its size
SMAC was played by me for three years straight, an hour at least every smurfing day
And finally, Diablo II. Not as much as Tav, thank god, but a fair amount all the same.