There are certain FPSs that play better (online) on the PC side mainly because they were primarily designed for the keyboard+mouse control and because they require much more precision in their aiming. Nothing, not even the Wiimote, has per-pixel accuracy like a keyboard+mouse do. Why do you think CS failed on the Xbox? There are certain FPSs out there where the key to becoming competent is burst-firing at the head and then quickly spinning around in mid-air to spray at the ground and get kills. Then you have the console side where the Halo model works and excels. Sticky-aim, aim-assist, and lower gravity make up for the slowness and overall lack of accuracy that comes with using the dual analog sticks.

From what I've read about Shadowrun is that the control scheme and gameplay mechanics are tilted in favor of the console gamer because certain features like mouse sensitivity are locked in within certain parameters.

While I enjoy playing single-player campaigns on either the PC or consoles (with the console benefiting from a more relaxed playstyle), I could never really play a console FPS onlne seriously. I want to know that all my kills are legitimate because I placed the reticle over the guy's head and blew him away, not that there's some aim-assist going on in the background which compensates for the lack of accuracy in the control scheme.