Lucrecia hasn't changed into Jenova. However, since Sephiroth was supposed to be the new 'embodiment' of Jenova's power, he was told that his mother was called Jenova; even when he found out he was mothered by a human woman, he still considered Jenova his real mother because she's the one whose essence had contributed the most to him.
The Jenova cells in Lucrecia's body kept her alive and strong, but they didn't transform into Jenova. She remained clinging to life and unable to die, even though she wanted to; she was still vaguely aware that Sephiroth was alive, too, thanks to the powers granted to her by Jenova's cells. She's still herself, though.Lucrecia has changed to Jenova 'cause Hojo's experiements keeping her cells alive/safe/fresh?Nah, he didn't need his own cells - only Jenova's cells, mako energy and someone who survive the combination of mako and Jenova with their mind intact. He never intended to make a perfect duplicate of Sephiroth; rather, he wanted to re-create the success of that earlier project, by producing someone similarly powerful. SOLDIER members come close, because they're far stronger and more powerful than regular humans, but Sephiroth represented an even stronger combination of human and Jenova, something that failed whenever Hojo tried to re-create it in his experiments on the Nibelheim survivors.Hojo wants to make copies of Sephy. Well for that he needs cells of his own and Jenova (Lucrecia from now on)?