Usually, my parents and sis don't bother me much; especially if I'm just trying to relax or playing a game/chatting with friends. I do get annoyed when people bother me when I'm watching something though.

I was watching Lost the other day, my favourite show...and seriously, someone knocked on the door...then someone rang me on my mobile, and basically I had to ignore everyone for 40 minutes so I could watch it. >_<