Quote Originally Posted by Tavrobel View Post
Differs greatly? TRC's anime was decently enjoyable, but not something I would rave about, as it suffers the general "shonen fill with crap to make money" syndrome. Generally, the faithful adaptations are better, so those are the ones I care about. As for the other way around, I would know even less.
It depends on the anime for me. Sometimes if liberties are taken they can turn out for the better. The end of the Sailor Moon saga introduces the Sailor Starlights, who play a way bigger role in the anime than they do in the manga, but it makes the show that much more awesome. Also, the beginning of season 2 has a story arc that doesn't exist in the manga, as the second arc of the manga was still being written as they released the second season of the anime.

I've never read the Rozen Maiden manga, but I've been told it's pretty different from the anime.