I don't think this will have much of an effect on people. Maybe for games that are not quite remembered for their excellent soundtracks (FPS, Platformers, and certain fighting games *cough Soul Calibur cough*) but RPGs are known for their soundtracks so I don't think they have too much to worry except for ones that have bad soundtracks :rolleyes2

I don't think SE should worry nor do I feel Uematsu's absence spells the end of good music in the FF series.