Blitzball... seriously their is nothing really as obnoxious as Blitz Ball. It nets you nothing worthwhile in terms of items, once your team gets a few levels or you hire good people, the difficulty of the game plummets to zero. To make it worse, its the only smurfing sidequest you have available until you get to the Calm Lands, 30 hours later in the game. My option is left to either playing the pointless Mini-game, or play through the atrocious story.

Tetra Master is also freaking annoying but at least IX had other good mini games and side quests to do so you could avoid it except for one story part. Its only made more frustrating by the fact we had played an excellent card game in VIII. Triple Triad rules.

Rosa's mini game In FFIV DS is also pretty ridiculous and stupid.

Chocobo Breeding is actually one of my favorite mini-games in the series. I just need to track down a Wonderful and train it with my Black to get my Gold. Course, all I need it for is KotR which I never use but I do make good use of the others.