I just got done playing my game on my college football game and was just starting to simulate the rest of the week. The California/Stanford game just got done simulating and California won and then lo and behold the power went off because it was storming a bit outside (luckily I already had my game saved so I didn't have to play it again). But then when I started the simulating over again California lost the game to Stanford and now they won't win the Pac 10 because the power went off for a split second.
The California Golden Bears have a right to be furious.
New topic: Bad experiences you've had with losing gameplay from not saving or losing savegames.