They'll probably pull an Electra and semi re-write the whole thing. Deadpool is an awesome character and I felt Ryan Reynolds did a fine job playing as him. The problem is how they smurfed up his origin which seems to be something they are going to keep (Deadpool has apparently gained the ability to copy other mutant powers. Something tells me Stan's been watching Heroes a wee bit )

Deadpool could be interesting if they decide to go the "avant garde" route and turn him into a bit of a satire piece like his comic series was. He used to break the fourth wall and make fun of other comic books while doing his own misadventures. He even died in his book and was replaced by four new Deadpools, poking fun at a different comics book legend...

Its got potential but I feel the film may have already been marred a bit. They'll probably make him more serious than he should be, just like Spider Man.