My prediction:

House and Cuddy will be about a 6 episode arc. I mean I'd love for them to be together and have a happy ending but it's not great writing or what you'd expect from the show.

I also think the final every episode (whenever that is, I haven't heard anything about it ending or anything) will have house dying or finally getting together with cuddy for good.

I also predict I will blub lots next season with the 13 storyline Also suspect 3rd team member dying will either put House back into the mad house or trigger startling revelation.