Ah, yeah, I didn't really use the 10mm (although alongside the Tranquilizer Gun, it was my most used gun), I just kept doing takedowns like crazy, even if it involved significant patience. Some bits were... awkward to say the least. I did use the 10mm for luring enemies, though.
I didn't have Typhoon until the second boss either, and used it for bosses and (SPOILER)saving Malik.