Hardcore:
Skydiving
Hang gliding
Class 5 river rafting
Helicopter over volcanos
Zorbing in New Zealand
Go to North Korea. Liberate North Korea.

Travel:
Visit every single state in the US, airport layovers don't count.
Roadtrip from West Coast to East Coast
Visit every continent, including Antarctica!
Rent a cabin for a month somewhere beautiful and isolated and disconnect from technology.
Safari trip in Africa
Spend 6 months visiting European countries

Random:
Appear on television at least once, hopefully not connection with crime and the daily news.
Hot air balloon ride
Shoot guns at a shooting range. Bang bang!
Meet a president or a member of a royal family
Bowl a perfect game
Witness a herd of wild horses galloping in a field
Go see a World Cup/Superbowl/Olympics in person.

Food:
Pick fresh strawberries from a strawberry field
Eat at Chez Panisse and French Laundry, two of the best restaurants in the world
Learn to make handmade pasta from a little old Grandma in Italy
Grow my own herb and vegetable garden

Personal:
Learn to play the piano
Learn to speak passable French, Italian & Spanish
Read all 100 of Newsweek's Top 100 Books of All Time
Donate time & effort to disaster relief.
Help build a house for Habitat for Humanity

Professional:
Publish work
Get hired by a celebrity. A & B list only.
Own a restaurant
Own and operate my own doggie rescue ranch.