Every Civilization or SMAC game I play ends in nuking. Planet busters are far more satisfying than nukes though. In fact, I recently reinstalled SMAC solely to unleash a flurry of planet busters.
And though I haven't played it recently, whenever I play through Half-life, Gordon Freeman is the only one who makes it out alive. Once a scientist or guard outlives their usefulness they experience the joy that is having a SPAS-12 unloaded in their face. Until I get the Egon gun anyway. Then I gib every single one.