I was a huge Spider-Man fan growing up, and I still have a troutton of Amazing Spider-Man comics somewhere. I know I shouldn't get too excited after the last trilogy, but this trailer looks promising. The Lizard is a bit of a quirky first villain for Spider-Man, but I can see the underlying story to it (with Dr. Connors being a sympathetic character) making a solid movie, as Vivi22 pointed out. It would work well with a second villain who arrives late on the scene, so I hope those rumors of two villains are true.