If it's done right, you probably won't notice it.

The Resident Evil REmake for GameCube, for example, had jiggle physics, but it had to be pointed out to me, and all my response was was "WOW THIS GAME'S GRAPHICS ARE AMAZING!"

Boobs jiggle in real life, boobs should jiggle within reason in games, if they're done right. But games like Azura's Wrath take the jiggling to a laughable level. The girls in that game look like they have tops full of jello.

But then, the exaggerated boobage is the least of that game's problems.