I use a combination of Chrome, Internet Explorer and Firefox at work for various things.

At home I'm still a Firefox girl at heart. I tried Chrome but it just didn't click with me and I also had issues with it crashing left right and center.

Although lately each new build of Firefox decides it hates Flash and I end up having to uninstall and reinstall Flash to get them to both co-operate again. Something probably goofed in my registry but I'm far too lazy to go hunting for it!