I'd be interested in a sequel so long as the gameplay wasn't complete trout this time. Everything about that game was pretty awesome except the actual combat.

Also, as long as Silicon Knights (or more specifically Dennis Dyack) didn't go anywhere near it, but since last I heard they were ruled against in their lawsuit against Epic, actually had to pay Epic a load of money, and were at the time a company of less than five people I'm really not too concerned they'll ever make anything again.