I'm just going to mention Pokémon, Digimon, Yu-Gi-Oh!, and Dragon Ball Z out of nostalgia.

In general, I simply go where the awesome is in shows. That being said, Fullmetal Alchemist: Brotherhood is amazing. I decided not to blow through it in one weekend, instead deciding to watch about two episodes per day. I knew the majority of the plot going in, but that did nothing to cheapen the experience for me. Sure, the first 10-15 episodes can drag a bit, but the series quickly ensnares you and doesn't let you go. The action moves at a quick and satisfying rate, and the themes are explored without being belabored and beaten to death. However, the characters are really its greatest strength. When you manage to create a cast where you care about even the minor characters (e.g. Knox), you know you're doing something right.

I'm actually almost finished with my first viewing of the series; I only have six episodes remaining to watch. If they're even half as good as I hear, it'll be a treat.