To clarify, in 1.x they started unique to the nation but once they hit the 'bigger stages' they all tied in together. I'd expect something similar. There are also smaller storylines for each of the guilds. The quests, of course, are there too. I imagine there will be a few miniature storylines over the course of 2-3 quests for some NPCs, as I'm pretty sure that was the case in 1.x...