I don't know, maybe you should start with the Ultimate line since it was kind of meant to be a modern reboot of the various Marvel franchises, I know Spider-Man is still kind of reeling with fans for the One More Day storyline which was not popular with any of the fanbase. Which is always been the books problems for the last 20 years which is that it does good and then things like the Clone Saga or One More Day show up and hurt the franchise for years.