I'd love another Metroid game...as long as it pretends Other M never happened. That game single-handedly destroyed the image of one of the strongest female video game protagonists there is...and we have precious few of those.

Another Legacy of Kain game would be nice. By that, I mean a proper one that continues the story, not this Nosgoth bullcrap Square Enix are bringing out.

I also want another Golden Sun game. Dark Dawn was awful, but it ended on an aggravating cliffhanger that promised more and, for all its faults, it DID introduce enough into the story to make me want more. Mourning Moon, please!