I actually went through that the other day...I was extremely lucky and scored the Alexander card on the first try, the Laguna card however, was a different story...it took about fifteen rounds for her just to play that card and each time she did use it I was "blessed" with a craptastic hand. Right now I am doing the Queen of Cards side quest and so far that is going fairly smoothly. *Knock on wood. I don't know what it is about this particular play through that I am accomplishing things easily that I haven't even bothered with on past plays.