I had one with VI when I was doing my very first play through back when I was at school. As you know the SNES game allowed you to save into 3 slot and I had one save with about 20 or so hours down in the WoR (I think I was at the part where you get Setzer and head to Daryl's Tomb). A day at school one of my friends was coming over to my house after school to do a homework assignment and after lunch he wanted to play and try VI for a bit (he loved RPGs) so I let him start a new file, he starts playing while I watch him and he is saving to his own file no problem then a few hours in (we were totally doing homework...really), he pressed up while saving and overwrote my save file by mistake.

I think my lifespan got shortened a few years that day...