I am not one of the standard targets for the MOBA genre. I play strictly co-op vs AI, as I largely hate (and suck at) competitive play. So I probably can't answer those questions.

But, going through the forums and looking at those who are members, a few things have come to consensus.

First, the game has some balance problems. Stitches is apparently by far the best hero, and you won't see a team without him. The talents fall into the same trouble that items and talent trees have in the past. Currently, most heroes do have a set build of "best talents". Which, especially since there is a balance problem with the heroes encouraging particular heroes over others, means that builds are very stagnant right now.

Second, while the competitive players aren't sure how the game is going to turn out long-run, they have agreed that this game has the greatest come-from-behind potential of any other major MOBA.