About 15 to 30 minutes depending on traffic (though if traffic is really light I can do it in as little as 10 minutes). I've fortunately never had a longer work commute than this.
I believe if I were to end up working somewhere that took longer than half an hour to drive to I'd have to move I start freaking when my commute has taken more than 20 minutes. I can't imagine how people who have an hour or more commute handle it.