If my wife has read it and thinks I'd like it, I probably will. She's my main source of books. For the sci-fi titles that aren't really her thing, I look through lists of best sci-fi or fantasy novels online. I'll also read the 'inside the cover' description as a check.
I don't give a smurf about titles or covers, and I've only been drawn in by the first sentence or page of a book a couple times. Some of the books I read need a few chapters to get going but are pretty good once they do.