The "You're Not Alone" Scene

[Depression Moon]

It was always my understanding that he's like brain-washed or zombiefied or something in that particular scene, which is why everyone is so adamant about telling him how loved he is. He's not just being angsty, he's being controlled by Garland to think his friends are enemies.

So no, the scene doesn't bother me.

Yeah. Right before that scene Garland says it's a shame he has to turn Zidane into a regular genome, so what that basically was was him slowly starting to lose his soul, but the interference of his friends prevented it from completing. Why Garland didn't keep him by his side when he knew Zidane came with seven other people, I'm not sure.