Decided to go with Vanguard to round out the biotic trio. I like Tali and Garrus so I don't have a problem including one of them in the missions for the tech specialty.
So far it's hard to get used to this first game after playing through the other two where the combat seems much more polished. Also the safe cracking mini game is stupid. I've played through the other games so I already know the main plot points but I was surprised that Saren was set up as the villain so quickly, but effectively.