You could maaaybe do like a Ivalice: Total War edition, I mean heck most of the plot of FFXII is inherently a power struggle between two nations.

Or, a SimCity: Midgar! Keep every sector's happiness, sanitation and order stats up to appease the people and win the day for Shinra! Reeve could be your advisor person.

Or do Spore: The FF Monster edition. How could one tiny life-form evolve to become a freaking behemoth and gain intelligence!

The possibilities are endless really!