SOME SPOILERS FOR OLDER AND NEW GAMES***

Suikoden - Teo McDohl. It really makes it hit home that your old life, family, city, all of it is the enemy now. It's the point where you really start to realize how far your party has come and how much has changed.

Suikoden II - Luca Blight. Epic boss fight. A lot of the time, games will pump up a boss to be super powerful and then you defeat it just like any other fight. But Luca just keeps going. It really shows just how monstrous and powerful he really is.

Omega Quintet - There's a boss fight against a man who is your friend, can't remember his name, but he turns in to this horrible, hideous monster and it was such a bright, lighthearted and silly game. So to see this grotesque figure that used to be a normal dude was pretty scary actually and a turning point for the game.

Tales of Graces f - The ending to the kid era. One character essentially dies, another vanishes, Asbel is scared straight, things between him and his friends kind of crumble after that. It was so bright and cheery and then BAM horrible thing happens, end era, fastforward 7 years later.

Breath of Fire III - Apparently I am a fan of mood whiplash. The first main boss of this game just recently really got me. It was again so lighthearted and bright and silly and you're fighting typical RPG monster. It runs away and you follow its blood trail and defeat it. Then you find out it was protecting a nest full of dead cubs that it was apparently feeding out of some weird kind of denial. My gosh.

Chrono Trigger - Atropos XR. The feels with her and Robo. THE FEELS

Xenosaga Episode III - The fight against Yuriev towards the end. Then Albedo arrives and things are all full of the feels. Likewise the fight against Pellegri and also the one against Virgil on disc 1.

Tales of the Abyss - Arietta. Not only is she strong as all heck, but I love her character and her story is so sad.

Fairy Fencer F - Marianna. My favourite character dies right after and it's a huge gut punch.

There are many more but those are the ones I can think of right now :3