My first playthrough took 118 hours, and I missed out on two whole confidants, and did not play in an optimized way at all. I missed out on a lot of stuff, actually. This game is unreal in its amount of content.
Replaying right now. Upthread I mentioned that in a trailer it sounded like Makoto's VA had been recast, but I just looked at the cast list and she hasn't. Thank goodness! Makoto's has the best female voice actor in the game.