You found a Seed of Defense!

[Vyk]

Yeah depends on the type of game. If it uses MMO rules like d Dragon Age and there is a dedicated tank to draw aggro then give him more defense. But if it's a normal game then I'll bring up a weak character since they can and will get hit, make them better capable of surviving

[Wolf Kanno]

It will largely depend on the game I'm playing. In most games I leave it for the end and simply forget about them. In MegaTen games on the other hand, I use them without hesitation.