The comics are better, storywise. Like Murder said, there's alot more stories to be told in a long-running comic book series that can't be touched in two feature length films. They're very different, but not as much as the X-men, where they all had generic costumes rather than the cool looking ones from the series.

I know Aunt May's been dead for awhile now, and Spidey has had issues with being cloned in the past.