Major graphical change, but only in clearity. PS resolution, 320x240 16-bit color. PC resolution (if you're PC is powerful enough), 640x480 32-bit color. This is just like with the GCN re-release of The Legend Of Zelda: Ocarina Of Time and Majora's Mask (but the GCN is only 24-bit color). With the better resolution, it looks a lot better.

Other than that, no, I don't think there's any other major changes (possiby a bug fix, like Zaphier said).