It's kinda pointless since most of us type with both hands the majority of the time. Basically the opposite side from the hand you are using is most difficult to type with because you're used to 1) not using your hand to type there and 2) not used to moving your hand about, much less the opposite hand. Capital letters on the opposite side is also annoying because you have to stretch your hand out. Yay.

But it is possible. I can probably type at 30 wpm with one hand. Maybe 40.