Install, run, it'll ask you if you want to check for updates, choose to do so, then click on "start", choose if you want a smart system scan (specific folders that are the usual target + the registry) or everything, or custom, or ADS (check the help file for details). Negligible entries are things like the last programs you ran list and stuff, ou can uncheck that one. Click on next and it'll scan, when it's done, you can review the findings and select which you want to quarantine/delete/keep.