Simply put, just post the weirdest game you have ever played.

I would have to say EarthBound (SNES).
I mean, come on, your neighbor's names are Picky and Pokey. How weird is that?

Katamari Damacy (PS2) Comes in second... it's just... I SWEAR, THEY HAD TO BE ON SOME CERTAIN SUBSTANCES TO MAKE THIS GAME.