I had the same problem Croyles ;( I had Squally_Leonharty tell me which bios & plugins to download, now every game I'm playing is running perfectly on it. As for the keyboard/controller. Mine didn't work at first, so I unplugged it uninstalled my software and then reinstalled them again. After that it seemed to work. You also have to make sure it's pad 1 you're configuring to :P

Edit: I have all the bios' available aparantly lol. and the plugins I currently have / am using are:

Graphics:
Petes D3D Driver 1.75
Sound:
Eternal SPU Plugin 1.47 (With Special Hacks on to stop fast music/make sound better with any FF games)
CD:
ePSXe CDR WNT/W2K Core 1.5.2