Quote Originally Posted by Prancing Mad
To be honest, I wasn't quite sure why it was bad. The game said it was, but, to be frank, I always gave 'em all a healthy dose. In fact, I had 99 of them in my item bin.
In Fury, (induced by Hypers) you take more damage in battle. In Sadness, (induced by Tranqs) you take less damage in battle. Also your attacks are greater in Fury and weaker in Sadness.

But yeah. I always use Hypers when I have them. If I only have a few, I save them for when I really need them. I try not to use them if I know a 'rest' will take place in the story. 'Cause 'rests' "cure" Fury and Sadness.