it is known that lucrecia gave birth to sephiroth, and that hojo is sephiroths father. it is also known that lucrecia loved vincent, and not hojo.

William Shakespeare wrote a poem called "The Rape of Lucrece" (which is rather long and can be found here if youre interested).

Significance? Maybe Lucrecia's story and Sephiroths creation is much more devistating than we first thought..