Talent wise? I honestly don't know, I'd have to be proficient at playing a variety of instruments to even be able to begin to think about a band's ability as a whole. As for who sounds the best to the most people, that's a simple as who's sold the most albums (Michael Jackson's Thriller sold the most worldwide). Influentially Elvis, The Clash, and Nirvana deserve mention because they essentially created or atleast popularized the genres I enjoy the most.