I don't play any instruments.
I used to get pain in my wrist before I was diagnosed with tendonitis after playing a game that requires constant and rapid button mashing for four or five hours, but it would always go away a few hours after I stopped playing. Right now, I have constant pain in my wrists no matter what I am doing (just worse when I'm typing or using a controller). If I can get it back to the pain just coming on after an hour or so of playing/computing, that would be good enough for me...
And yes, I do wear the wrist braces while I sleep, though I loosen them to let the blood flow better.