Seeing Nom's screenshot made me decide to start up a random minor side-discussion in this thread:

How do you organize your inventory and stash? Where do you keep your cube?

I keep my Tome of Town Portals in the upper-right corner of my inventory with my keys, then work my way back to the left with charms, leaving 8-16 spaces, or 2-4 columns, free to pick up items. In my stash, I keep my cube in the upper-right or upper left corner, with gems organized by column at the bottom of the stash, skulls and runes at the top next to the cube, and other items in the middle.