Kill Sephiroth... no wank.

[blackmage_nuke]

Kefka

Chuck N0rris

Raoul Duke

[Jowy]

gogo Luca Blight!

[JKTrix]

Kurosaki Ichigo.

Hell, any of the captain-level shinigami from Bleach.

lol and yes. Kuchiki Byakuya would probably be one of the more interesting matches.

Also, Goku. Ryu Hayabusa could probably take 'im out too.

[Little Blue]

Spock (if you don't consider being a half Vulcan, and admittedly superior to almost all humans, a super human advantage)

Bart Simpson

Itchy (possibly Scratchy too, if you ignore that they're a mouse and a cat)

John Chriton

Captain Pike (either before or during his life in a wheelchair)

Kirk however would get beaten so badly...

Gareth Martinez (From the Dread Empires Fall books)

I would say Scorpio from Alastair Reynolds books, but he's a hyperpig so I doubt he counts...

Yossarian (Catch-22, but he might just run away instead...)

That's all I can think of for now.

[Ichimonji]

Jean Grey. X-3 version.

So, you mean Phoenix. And yes, she would deliver some serious ownage.

[Cookie]

Wolverine
Lu Bu
Ma Chao
Snake
Dante
Me
Cloud
Omega Weapon from VIII

[Twilight Edge]

The Samoan Bulldozer, Umaga.

(for anyone who watches wrestling)

Samoan Spike. OUCH.

[I Am Stoner]

Vegeta, M Bison, Cloud(Duh), Diablo, Ajax, Neo.

[Dreddz]

Sol Badguy, Venom ( Guilty Gear ), Batsu, Haohmaru and Genjuro.

[Ryushikaze]

With the standards given, there are literally tons of folks who could down Sephiroth. In the grand scheme, he's actually low to middling on the charts. Han Solo could take him out.

Kuja and Zidane could do it without breaking a sweat.

Void mentioned several Saga characters, but forgot to mention Kos-mos, Jin, Shion, and even Momo could probably do it (energy arrows, natch)

A lot of Tales series characters...

He's not a bad swordsman, but he's nowhere near as nifty as the fandom wants it to be.

The real question isn't who can kill Sephypoo, but "why is this some incredible feat"?

[Christmas]

His Mama.

[escobert]

Cid!

[Roto13]

Proteus from X-Men.

[Captain Maxx Power]

Some spikey blonde haired kid with a minority complex.

[ljkkjlcm9]

My right big toe, all by itself.

I seriously think sephiroth is blown out of proportion, a lot. What can he do that's so awesome. He wields a long thin sword, and has a few good spells, the best of which he can only do with a special materia. Sorry but not that special really.

Megaman and anyone from that series could own him

THE JACKEL