I play guitar and I will say that it can help you a little in the understanding of the mechanics of the game but playing this is quite different than actually playing a guitar.
yeh...i didnt have problems with th eleft hand sequences really....strange coordination thing though...and i htink the blue button was kinda bust...so it didnt work to good....sometimes youd push it and it missed the note....cuz it was kinda sticky..but other then that..cool game....better then singstar...but it was disappointin when i found out the guitar wasnt as elaborate as i thought...but its cool...