Hell naw. It's MUCH easier to get a decent chain going if you use three characters with Quickenings. I killed a boss today with a chain of 8 quickenings without using any other attacks. Remember, one character can use his or her quickening(s) multiple times in a single chain. Also remember that you have to press the button twice if it says "Mist Charge"!
Well, I'm going off of the fact that Vengeful Ronin doesn't quite know how to chain Quickenings yet. When I was battling Ghis, I was only just getting the hang of quickenings.

If he can chain them all into one massive Quickening, then more power to 'em. I just know how I did it. Hell, I'm just now trying to figure out the whole Demon Wall thing.