The freaks from Metal Gear 2.

Black Color, the NASA Ninja in grey.
Running Man, the world's fastest mercenary!
Red Blaster, an explosion maniac in red! (He wears green)
Ultrabox, a trio of close-quarter assassins who erm...shoot you from afar.

Pure genius, I like to think that Metal Gear 2's assortment of weirdos were used as a template for future games.