http://gameboy.ign.com/articles/708/708063p1.html
In an interview with Reuter's yesterday, Nintendo President Satoru Iwata said there may not be a successor to the Game Boy Advance.
"I would have a second thought about using our resources on what would be the next generation of Game Boy Advance, considering the strong support DS is now enjoying," Iwata said. "The Japanese game market is now evolving around DS. We don't need to do something that will pour cold water on the situation."
The news is significant as the Game Boy is the longest-running game system ever. Launched in 1989, the Boy and its many iterations have sold over 120 million units.
At its E3 booth this year, Nintendo is not showing any Game Boy or Gamecube games.